Yes, HMRC have explicitly said that recording businesses records digitally can be recorded in Excel spreadsheets providing that they are digitally linked. In order for a spreadsheet to be complaint with MTD, the initial input of the data in the first instance can be inputted manually. Any further transfer, recapture or modification of that data must be done using digital links. A digital link in this instance would simply be a formula linking a cell from one sheet to another. The use of copying and pasting, or manually creating a VAT return is not compliant with MTD VAT.
Spreadsheets are permitted under the most recent legislation VAT Notice 700/22: Making Tax Digital for VAT Published 13 July 2018 under s 3.2.